Wednesday, 15 January 2014

State of the Nation’s Waistline report

The purpose of the State of the Nation’s Waistline report is to audit the state of obesity in the UK, to identify what initiatives and policy exists, and to assess their effectiveness in tackling obesity and weight management issues (National Obesity Forum)

Re-analysis of study of pancreatic effects of incretin therapy: Methodological deficiencies

We find that the data presented in the Butler paper have serious methodological deficiencies that preclude any meaningful conclusions (Diabetes, Obesity and Metabolism)

The effect of alogliptin and pioglitazone combination therapy on various aspects of beta-cell function in patients with recent-onset type 2 diabetes

Short-term treatment with ALO/PIO or ALO improved glycemic control in well-controlled T2DM patients, but only combined ALO/PIO improved beta-cell function. These data support that initial combination therapy with a DPP-4 inhibitor and TZD to address multiple core defects in T2DM may be a sensible approach (European Journal of Endocrinology)

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