Friday, 7 February 2014

Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease

Our study demonstrates that patients with type 2 diabetes have higher circulating levels of cyclophilin A than the normal population. Plasma cyclophilin levels were increased in patients with diabetes and coronary artery disease suggesting a role of this protein in accelerating vascular disease in type 2 diabetes (Cardiovascular Diabetology)

Insulin pump use in young children in the T1D Exchange clinic registry is associated with lower hemoglobin A1c levels than injection therapy

These data support the use of insulin pumps in this youngest age group, and suggest that metabolic control may be improved without increasing the frequency of severe hypoglycemia, but care should be taken as to the possibly increased risk of DKA (Pediatric Diabetes)

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