Monday, 31 March 2014

Microvesicles and diabetic complications - novel mediators, potential biomarkers and therapeutic targets

MVs contribute to the development of diabetic macrovascular and microvascular complications. In addition, clinical studies have indicated that changes in MV number and composition may reflect the pathophysiological conditions of disease, and therefore, may serve as potential biomarkers for diagnostic and prognostic use (Acta Pharmacologica Sinica)

Nonalbuminuric proteinuria as a biomarker for tubular damage in early development of nephropathy with type 2 diabetic patients

These findings suggest that urinary nonalbumin protein (NAP) reflects tubular damage in the early-stage type 2 diabetic nephropathy. We suggest that urinary NAP could be used as a biomarker for tubular damage in clinical practice (Diabetes/Metabolism Research and Reviews)

Bariatric Surgery versus Intensive Medical Therapy for Diabetes: 3-Year Outcomes

Among obese patients with uncontrolled type 2 diabetes, 3 years of intensive medical therapy plus bariatric surgery resulted in glycemic control in significantly more patients than did medical therapy alone (NEJM)

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