Monday, 28 July 2014

Metabolic profiles and treatment gaps in young-onset type 2 diabetes in Asia (the JADE programme): a cross-sectional study of a prospective cohort

In clinic-based settings across Asia, one in five adult patients had young-onset diabetes. Compared with patients with late-onset diabetes, metabolic control in those with young-onset diabetes was poor, and fewer received organ-protective drugs (The Lancet)

Bariatric surgery: implications for primary care

GPs play a pivotal role in the management of obesity with early referral of motivated individuals who have failed to achieve substantial weight loss (British Journal of General Practice)

Early pregnancy metabolite profiling discovers a potential biomarker for the subsequent development of gestational diabetes mellitus

The current pilot study found that itaconic acid may have potential as a novel biomarker in early pregnancy to predict the subsequent development of gestational diabetes mellitus (Acta Diabetologica)

Effect of Glycemic Control on Nocturnal Arterial Oxygen Saturation. A case-control study in Type 2 Diabetic patients

Glycemic control improvement significantly reduces the increased number of nocturnal oxygen desaturations that exist in type 2 diabetes (Journal of Diabetes)

Blood pressure and heart failure risk among diabetic patients

The current study suggests a U-shaped association between observed BP and the risk of HF among diabetic patients (International Journal of Cardiology)

Diabetes, antidiabetic medications and pancreatic cancer risk: an analysis from the international pancreatic cancer case-control consortium

This study provides the most definitive quantification to date of an excess risk of pancreatic cancer among diabetics. It also shows a 30% excess risk persists for more than two decades after diabetes diagnosis, thus supporting a causal role of diabetes in pancreatic cancer. Oral antidiabetics may decrease risk of pancreatic cancer risk, whereas insulin showed an inconsistent duration-risk relationship (Annals of Oncology)

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