Tuesday, 30 September 2014

Acknowledging and allocating responsibility for clinical inertia in the management of Type 2 diabetes in primary care: a qualitative study

In order to understand and address the problem of clinical inertia, provider, patient- and system-level barriers should be considered together rather than as separate issues. Acknowledgement of responsibility should be regarded positively as a motivator for change (Diabetic Medicine)

Serum neuron-specific enolase is elevated as a novel indicator of diabetic retinopathy including macular oedema

Serum neuron-specific enolase is elevated in and indicative of diabetic retinopathy. Neuron-specific enolase may be a potential biomarker of diabetic retinopathy (Diabetic Medicine)

Low-Dose vs Standard-Dose Insulin in Pediatric Diabetic Ketoacidosis

Low dose is noninferior to standard dose with respect to rate of blood glucose decrease and resolution of acidosis (JAMA Pediatrics)

Mortality and Incidence of Renal Replacement Therapy in People With Type 1 Diabetes Mellitus-A Three Decade Long Prospective Observational Study in the Lainz T1DM Cohort

A clear linear relationship between early glycemic control and the later development of end stage renal disease and mortality has been found (Journal of Clinical Endocrinology & Metabolism)

Liraglutide and the Preservation of Pancreatic ß-Cell Function in Early Type 2 Diabetes: The LIBRA Trial

Liraglutide provides robust enhancement of ß-cell function that is sustained over 48 weeks in early T2DM but lost upon cessation of therapy (Diabetes Care)

GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

The relative importance of the GLP-1 and insulin response versus improvement in insulin action in the liver and skeletal muscles for the glucose tolerance after RYGB and SG depends on when the patients are studied after surgery (Diabetes)

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