Thursday, 25 September 2014

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

Our results link non-caloric artificial sweeteners consumption, dysbiosis and metabolic abnormalities, thereby calling for a reassessment of massive NAS usage (Nature)

Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes

The benefits with respect to mortality that had been observed among patients originally assigned to blood-pressure–lowering therapy were attenuated but still evident at the end of follow-up. There was no evidence that intensive glucose control during the trial led to long-term benefits with respect to mortality or macrovascular events (NEJM)

Glucagon-Like Peptide 1 Receptor Agonist or Bolus Insulin With Optimized Basal Insulin in Type 2 Diabetes

Adding exenatide to titrated glargine with metformin resulted in similar glycemic control as adding lispro and was well tolerated. These findings support exenatide as a noninsulin addition for patients failing basal insulin (Diabetes Care)

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