Friday, 10 October 2014

Initial combination of linagliptin and metformin compared with linagliptin monotherapy in newly diagnosed type 2 diabetes patients with marked hyperglycaemia

These results support early combination treatment strategies and suggest newly diagnosed, significantly hyperglycaemic individuals may be effectively managed with oral, non-insulin therapy (Diabetes, Obesity and Metabolism)

Distinct HbA1c trajectories in a type 2 diabetes cohort

Four subgroups with distinct HbA1c trajectories were identified. More than 90 % reached and maintained good glycemic control (subgroup one and two). Patients within the two subgroups that showed a more unfavorable course of glycemic control were younger, had higher HbA1c levels and a longer diabetes duration at baseline (Acta Diabetologica)

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