Friday, 5 December 2014

Effect of Statin Therapy on Incident Type 2 Diabetes Mellitus in Patients with Clinically Manifest Vascular Disease

Statin use increases the risk of incident T2DM in patients with clinically manifest vascular disease. The increase in risk was independent of the number of metabolic syndrome criteria, and was even more pronounced in patients with low baseline glucose levels (American Journal of Cardiology

Maternal body size prior to pregnancy, gestational diabetes and weight gain: associations with insulin resistance in children at 9–10 years

Maternal body size prior to pregnancy is positively associated with increases in child insulin resistance, at least until the ‘obese’ category is reached. This is independent of gestational diabetes and not mediated by body size of the child, suggesting genetic and/or developmental programming origins (Diabetic Medicine)

Years of life lost and healthy life-years lost from diabetes and cardiovascular disease in overweight and obese people: a modelling study

Our estimations for both healthy life-years and total years of life lost show the effect of excess bodyweight on cardiovascular disease and diabetes, and might provide a useful health measure for discussions between health professionals and their patients (The Lancet Diabetes & Endocrinology)

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